Mechanistic insights into cAMP-mediated presynaptic potentiation at hippocampal mossy fiber synapses
Presynaptic plasticity is an activity-dependent change in the neurotransmitter release and plays a key role in dynamic modulation of synaptic strength.Particularly, presynaptic potentiation mediated by cyclic adenosine monophosphate (cAMP) is widely seen across the animals and thought to contribute to learning and memory.Hippocampal mossy fiber-CA3